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Biology

INTRODUCTION TO SYSTEMS BIOLOGY, Indian Reprint 2018 - URI ALON

Author

URI ALON

Cover Price : Rs 1,995.00

Imprint : T & F / Routledge
ISBN : 9781498770903
YOP : 2018

Binding : Paperback
Total Pages : 416
CD : No

"...Alon boldly articulates the basic principles underlying biological circuitry at different levels and shows how powerful they can be in understanding the complexity of living cells. For anyone who wants to understand how a living cell works, but thought they never would, this book is essential." —Michael B. Elowitz, California Institute of Technology, Pasadena, USA "This is a remarkable book that introduces not only a field but a way of thinking....Alon’s clear intuitive language and helpful examples offer — even to a mathematically naive reader — deep mathematical insights into biology. The community has been waiting for this book; it was worth the wait." —Galit Lahav, Harvard Medical School, Boston, USA "Uri Alon offers a highly original perspective on systems biology, emphasizing the function of certain simple networks that appear as ubiquitous building blocks of living matter. The quest for simplicity — without losing contact with complex reality — is the only way to uncover the principles organizing biological systems. Alon writes with uncommon lucidity…" —Boris Shraiman, University of California, Santa Barbara, USA An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to askwhy a system is designed in a particular way and then proceeds to answer with simplified models. Features • Explains the elementary circuits in transcription regulation, signal transduction, and developmental networks • Examines the principle of robustness • Details how evolutionary optimization can be used to understand optimal circuit design • Considers how kinetic proofreading and other mechanisms can minimize errors in biological information processing • Includes exercises, solved problems, and appendices with background material Contents INTRODUCTION TRANSCRIPTION NETWORKS, BASIC CONCEPTS AUTO-REGULATION, A NETWORK MOTIF THE FEEDFORWARD LOOP NETWORK MOTIF TEMPORAL PROGRAMS AND THE GLOBAL STRUCTURE OF TRANSCRIPTION NETWORKS NETWORK MOTIFS IN DEVELOPMENTAL, SIGNAL-TRANSDUCTION AND NEURONAL NETWORKS ROBUSTNESS OF PROTEIN CIRCUITS, THE EXAMPLE OF BACTERIAL CHEMOTAXIS ROBUST PATTERNING IN DEVELOPMENT KINETIC PROOFREADING OPTIMAL GENE CIRCUIT DESIGN RULES FOR GENE REGULATION BASED ON ERROR MINIMIZATION EPILOGUE: Simplicity in Biology APPENDIX A: The Input-Function of a Gene, Michaelis-Menten and Hill Equations APPENDIX B: Multi-Dimensional Input-Functions APPENDIX C: Graph Properties of Transcription Networks APPENDIX D: Cell-Cell Variability in Gene Expression GLOSSARY BIBLIOGRAPHY Professor Uri Alon is at the Weizmann Institute of Science, Rehovot, Israel.

Botany, 2nd ed - V. Verma

Author

V. Verma

Cover Price : Rs 550.00

Imprint : Ane Books Pvt. Ltd.
ISBN : 9789382127086
YOP : 2015

Binding : Paperback
Total Pages : 1084
CD : No

About the Book :- The present book is an attempt to provide a detailed account of different branches of botany for the students of degree classes, plus II classes and also for those who are appearing in different competitive examinations. The subject-matter of the book has been well supplemented with high quality and adequately labelled illustrations. A new chapter on Mutation has been added along with an appendix giving latest information about the regulation of gene activity. Contents :- Unit I-Plant Kingdom : 1.Biological Classification; 2.Viruses; 3.Monera (Bacteria); 4.Monera (Cyanobacteria); 5.Protista; 6.Algae ;7.Fungi; 8.Lichens; 9.Bryophyta; 10.Pteridophyta; 11.Gymnosperms; Unit II-Angiosperms :-12.The Reproduction of Flowering Plants; Unit III-Morphology 13.Vegetative Morphology; 14.Reproductive Morphology; Unit IV-Systematics 15.Systematics; Unit V-Plant Anatomy 16.Plant Anatomy;Unit VI-Cell Biology 17.The Cell:The Basic Unit of Life;Unit VII-Genetics 18.Mendel and His Laws of Inheritance; 19.Structure and Function of Genetic Material; 20.Plant Breeding and Crop Improvement; 21.Genetic Engineering, Cloning and Genomics;Unit VIII-Plant Physiology :-22.Plant Water Relations; 23.Absorption of Water; 24.Ascent of SAP; 25.Transpiration; 26.Mineral Nutrition; 27.Photosynthesis; 28.Translocation of Organic Solutes; 29.Respiration; 30.Nitrogen Metabolism; 31.Growth and Growth Hormones; 32.Physiology of Flowering; 33.Plant Movements; Unit IX-Ecology :-34.Organisms and Environment; 35.Biotic Community and Plant Succession; 36.Ecosystem; 37.Biodiversity and Conservation; 38.Natural Resources;39.Environmental Pollution; Unit X-Economic Botany :-40.Plants of Economic Importance; Unit XI-Origin of Life :-41.Origin of Life; Unit XII-Organic Evolution :-42.Evidences and Theories of Organic Evolution;43. Mutation, Appendix, Index. About the Author :- Dr.V.Verma is an aluminus of some very illustrious Institutions of India, namely, K.P.Inter College, Allahabad, Ewing Christian College, Allahabad, University of Allahabad and University of Delhi for more than forty years. His books, numbering about a dozen, have been widely appreciated by students and teachers of undergraduate as well as postgraduate classes of all Indian Universities. His books have been written in a very lucid style and in an easily understandable language. After retiring from Delhi University, he has joined Amity Institute for Competitive Examinations as Professor and Head of the Botany Department.

MOLECULAR CELL BIOLOGY, 7TH ED - HARVEY LODISH

Author

HARVEY LODISH
ARNOLD BERK
CHRIS A. KAISER
MONTY KRIEGER

Cover Price : £ 59.99

Imprint : Palgrave / Macmillan
ISBN : 9781464109812
YOP : 2013

Binding : Hardback
Total Pages : 1246
CD : No

Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. These examples include the HPV vaccine and its ability to protect against common types of HPV (Chapter 4), potential treatment of cystic fibrosis using small molecules (Chapter 11), and variations in human sense of smell (Chapter 22). An experienced teachers of both undergraduate and graduate students, the author strive to balance coverage of exciting new developments in the field-like induced pluripotent stem (iPS) cells (Chapter 21)-with tools that help students learn and practice what they’ve learned. In addition to end-to-section summaries and a list of key terms for self-study, a robust set of end-of-chapter problems includes analyze the Data problems, which give students experience interpreting experimental evidence. Contents -Molecules, Cells, and Evolution -Chemical Foundations -Protein Structure and Function -Basic Molecular Genetic Mechanisms -Molecular Genetic Techniques -Genes, Genomics, and Chromosomes -Transcriptional Control of Gene Expression -Post-Transcriptional Gene Control -Culturing, Visualizing, and Perturbing Cells -Biomembrane Structure -Transmembrane Transport of Ions and Small Molecules -Cellular Energetics -Moving Proteins into Membranes and Organelles -Vesicular Traffic, Secretion, and Endocytosis -Signal Transduction and G Protein-Coupled Receptors -Signaling Pathways that Control Gene Expression -Cell Organization and Movement I: Microfilaments -Cell Organization and Movement II: Microtubules and Intermediate Filaments -The Eukaryotic Cell Cycle -Integrating Cells into Tissues -Stem Cells, Cell Asymmetry, and Cell Death -Nerve Cells -Immunology -Cancer

Plant Biology

Author

Alison M. Smith
George Coupland
Liam Dolan
Nicholas Harberd

Cover Price : £ 53.00

Imprint : Garland Science
ISBN : 9780815340256
YOP : 2010

Binding : Paperback
Total Pages : 680
CD : No

About the Book: The sunlight that is captured by photosynthetic organisms is the energy source that ultimately fuels almost all of the lift on earth. Plants are by far the predominant land-based photosynthetic organisms, and provide the energy that supports almost all of earth’s ecosystem. An understanding of the biology of plants is therefore one of the most important goals of contemporary science, a goal that becomes increasingly pressing as human-generated changes in the earth’s environment threaten ecosystem stability. Plant Biology is a ‘where we are now’ account of plant science. It acknowledges the distinguished history of the subject, but its approach is strongly influenced by the radically new outlook that has emerged in the last twenty years. Many of the recent advances in plant biology the author describe are useful in the understanding of modern biology as a whole. Contents: Chapter 1: Origins Chapter 2: Genomes Chapter 3: Cells Chapter 4: Metabolism Chapter 5: Development Chapter 6: Environmental Signals Chapter 7: Environmental Stress Chapter 8: Interactions with other Organisms Chapter 9: Domestication and Agriculture

Physical Biology of the Cell, 2nd ed.

Author

Rob Phillips
Jane Kondev
Julie Theriot
Hernan G. Garcia

Cover Price : £ 69.00

Imprint : Garland Science
ISBN : 9780815344506
YOP : 2013

Binding : Paperback
Total Pages : 1088
CD : No

Physical Biology of the Cell maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that unite a given set of biological phenomena. Herein lies the central premise: that the appropriate application of a few fundamental physical models ca n serve as the foundation of whole bodies of quantitative biological intuition, useful across a wide range of biological problems. The Second Edition features full-color illustrations throughout, two new chapters on the role of light in life and pattern formation, additional explorations of biological problems using computation, and significantly more end-of-chapter problems. This textbook is written for a first course in physical biology or biophysics for undergraduate or graduate students. Contents. Preface Acknowledgments Special Sections Map of the Maps Part I The Facts of Life 1. Why: Biology By the Numbers 2. What and Where: Construction Plans for Cells and Organisms 3. When: Stopwatches at Many Scales 4. Who: "Bless the Little Beasties" Part II Life at Rest 5. Mechanical and Chemical Equilibrium in the Living Cell 6. Entropy Rules! 7. Two-State Systems: From Ion Channels to Cooperative Binding 8. Random Walks and the Structure of Macromolecules 9. Electrostatics for Salty Solutions 10. Beam Theory: Architecture for Cells and Skeletons 11. Biological Membranes: Life in Two Dimensions Part III Life in Motion 12. The Mathematics of Water 13. A Statistical View of Biological Dynamics 14. Life in Crowded and Disordered Environments 15. Rate Equations and Dynamics in the Cell 16. Dynamics of Molecular Motors 17. Biological Electricity and the Hodgkin-Huxley Model 18. Light and Life Part IV The Meaning of Life 19. Organization of Biological Networks 20. Biological Patterns: Order in Space and Time 21. Sequences, Specificity and Evolution 22. Whither Physical Biology? Index

Integrative Organismal Biology - Lynn B.Martin

Author

Lynn B. Martin
Cameron K. Ghalambor
H. Arthur Woods

Cover Price : $ 129.95

Imprint : Wiley
ISBN : 9781118398784
YOP : 2015

Binding : Paperback
Total Pages : 354
CD : No

Integrative Organismal Biology synthesizes current understanding of the causes and consequences of individual variation at the physiological, behavioral and organismal levels. Emphasizing key topics such as phenotypic plasticity and flexibility, and summarizing emerging areas such as ecological immunology, oxidative stress biology and others, Integrative Organismal Biology pulls together information across a multitude of disciplines to provide a synthetic understanding of the role of the individual in evolution. Beginning with grounding theory highlighting the role of the individual in evolutionary and ecological processes, the book covers theory and mechanism from both classic and modern perspectives. Chapters explore concepts such as how genetic and epigenetic variation becomes physiological and phenotypic variation, homeostasis, gene regulatory networks, physiological regulatory networks. A concluding section illustrates these concepts through a series of case studies of life processes such as aging, reproduction, and immune defense. Written and edited by leaders in the field, Integrative Organismal Biology is an important advanced textbook for students and researchers across a variety of subdisciplines of integrative biology. -Unique focus on how genetic and environmental variation in individuals mediates physiological and phenotypic variation - Emphasizes hot topics including phenotypic plasticity and flexibility, physiological complexity, ecological immunology, and oxidative stress biology - Covers eco-evolutionary theory and mechanism from both classic and modern perspectives - Written and edited by leaders in the field Contents Acknowledgments Notes on Contributors 1 PLASTICITY, COMPLEXITY, AND THE INDIVIDUAL Cameron K. Ghalambor, Lynn B. Martin, and H. Arthur Woods Introduction Bridging the Conceptual Divide Integrative Organismal Biology: Progress to Date Phenotypic Plasticity: The Link between Individuals, Environments, and Evolution The Problem of Complexity Embracing the Individual and the Union of Functional and Evolutionary Biology Conclusion References 2 THE ECOLOGICAL AND EVOLUTIONARY IMPORTANCE OF VARIATION IN LIFE HISTORY REACTION NORMS Daniel H. Nussey Introduction The Reaction Norm Approach and Individual by Environment Interactions (I × E) Why Do Reaction Norms Vary? Causes and Consequences of Variation in Avian Phenological Plasticity Integrating Field and Laboratory Studies of Life History Plasticity The Challenges Ahead References 3 CURVE-THINKING: UNDERSTANDING REACTION NORMS AND DEVELOPMENTAL TRAJECTORIES AS TRAITS Joel Kingsolver, Sarah Diamond, and Richard Gomulkiewicz Introduction Characterizing Curves Variation among Curves Simplicity and Biological Hypotheses Summary and Future Directions Acknowledgments References 4 PLASTICITY AND PERSONALITY Kimberley J. Mathot and Niels J. Dingemanse Animal Personality: Moving beyond Optimality and Embracing Individual Differences Individual Differences in Behavioral Plasticity Personality-Related Differences in Plasticity Adaptive Explanations for Personality-Related Differences in Plasticity Ecological and Evolutionary Implications of Personality and Plasticity Genetic and Environmental Underpinnings Designs to Study Personality-Related Differences in Plasticity Conclusions and Future Directions References 5 INDUCTION AND FUNCTION OF POLYPHENIC MORPHS: PROXIMATE REGULATORY MECHANISMS AND EVOLUTIONARY IMPLICATIONS Anthony J. Zera and Jennifer A. Brisson Introduction Background on Endocrinology and Gene Regulation Case Studies Summary and Future Directions Acknowledgments References 6 EVOLUTIONARY SYSTEMS BIOLOGY: SHIFTING FOCUS TO THE CONTEXT-DEPENDENCY OF GENETIC EFFECTS Mihaela Pavli¡cev and Günter P. Wagner Introduction Two Ends of the Spectrum in Evolutionary Biology Context-Dependency in Population Genetics: Epistasis Genetic Effects Structured by Development: Pleiotropy What Are the Consequences of Context-Dependency? Generalizing SPC Model: Interaction of Gene Effects, or Effects of Interactions? Conclusion References 7 THE ROLE OF ECOLOGICAL EPIGENETICS IN INTEGRATIVE BIOLOGY Aaron W. Schrey, Joshua Banta, Holly J. Kilvitis, and Christina L. Richards Introduction Ecological Epigenetics Case Study: Arabidopsis Thaliana Conclusion References 8 AN ELEPHANT IN THE FOG: UNIFYING CONCEPTS OF PHYSIOLOGICAL STASIS AND CHANGE H. Arthur Woods and J. Keaton Wilson Introduction Elaborations of Stasis and Change Axes of (Dis)similarity Constructing a Conceptual Elephant Unification Diffuses Concepts and Tools Costs and Constraints Conclusion Acknowledgments References 9 PHYSIOLOGICAL REGULATORY NETWORKS: THE ORCHESTRA OF LIFE? Lynn B. Martin and Alan A. Cohen Introduction What is a Physiological Regulatory Network (PRN)? Known and Expected Characteristics of PRNs Organismal Implications of PRNs: Stability and Resiliency Ecological and Evolutionary Implications of PRNs: Constraints and Evolvability Open Issues Conclusion Glossary References 10 INTEGRATING COSTS OF REPRODUCTION BETWEEN THE SEXES Robert M. Cox Introduction Integrating Costs of Reproduction through Common Currencies Intralocus Sexual Conflict and Life-History Evolution Immunocompetence Handicaps and Sex-Specific Costs Integrating Sex-Specific Processes through Shared Regulatory Axes Summary Acknowledgments References 11 IMMUNE SYSTEMS: LINKING ORGANISMS, POPULATIONS, AND EVOLUTION THROUGH DISEASE James S. Adelman Introduction Immune Systems: A Brief Overview Proposed Divers of Immune Heterogeneity Consequences of Immune Heterogeneity: Theoretical Studies Consequences of Immune Heterogeneity: Empirical Studies Bridging the Divide between Theory and Experiment Acknowledgments References 12 DEVELOPMENTAL PLASTICITY OF INDIVIDUAL VARIATION IN STRESS RESPONSES Haruka Wada Introduction When is a Change in Environment a Stressor? Organismal Responses to Stressors Integrating Developmental Plasticity Future Directions Conclusion References 13 A COMMON FRAMEWORK FOR THE REGULATION OF GROWTH AND SIZE: STEPPING AWAY FROM THE TREES TO SEE THE FOREST Goggy Davidowitz and Bryan R. Helm Introduction A General Framework for the Regulation of Growth and Body Size Commonalities in the Regulation of Body Size Across Taxa Using the Framework to Address the Ecology and Evolution of Growth and Size Acknowledgments References 14 ADDING FUEL TO THE “FIRE OF LIFE”: ENERGY BUDGETS ACROSS LEVELS OF VARIATION IN ECTOTHERMS AND ENDOTHERMS Vincent Careau, Shaun S. Killen, and Neil B. Metcalfe Introduction Intrinsic Factors that Explain Variation in MR Extrinsic Factors that Explain Variation in MR Energy Budgets Metabolic Scopes: A Different Kind of Energetic Budgeting Energetic Constraints on Individual Behavior Conclusions and Future Perspectives References 15 BIOLOGICAL TIMEKEEPING: INDIVIDUAL VARIATION, PERFORMANCE, AND FITNESS Scott A. MacDougall-Shackleton, Heather E. Watts, and Thomas P. Hahn Introduction Endogenous versus Environmental Drivers Responses to Entrainment by Endogenous Clocks Varies over Their Cycle General Properties of Biological Rhythms Circadian Rhythms Circannual Cycles and Seasonality Conclusion Acknowledgments References 16 SENESCENCE: INTEGRATING BIOLOGY FROM CRADLE TO THE GRAVE Mark F. Haussmann and Lisa A. Treidel Introduction Ultimate Theories of Aging Proximate Theories of Aging Future Directions References 17 LINKING PHYSIOLOGY, CLIMATE, AND SPECIES DISTRIBUTIONAL RANGES Francisco Bozinovic and Daniel E. Naya Introduction Limits to Geographic Ranges: Examples Involving Capacities and Tolerances Limits to Geographic Ranges: Examples Involving Tolerances and Plasticity Proximate Causes behind Macrophysiological Patterns Conclusions and Future Directions Acknowledgments References 18 TRADE-OFFS AND BIOLOGICAL DIVERSITY: INTEGRATIVE ANSWERS TO ECOLOGICAL QUESTIONS Paul R. Martin Introduction Evolutionary Trade-Offs and the Distributions of Species Are Trade-Offs Universal? Trade-Offs, Integrative Biology, and Moving Forward Acknowledgments References 19 CONCLUSIONS: THE CENTRAL ROLE OF THE ORGANISM IN BIOLOGY H. Arthur Woods, Lynn B. Martin, and Cameron K. Ghalambor Introduction How Do Complex Traits Interact with Complex Environments? Where Does Organismal Diversity Come From and How Does It Evolve? How Useful is Reductionism? What are the Consequences of Emergence for Organismal Biology? Conclusions to the Conclusions Acknowledgments References Index


   

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