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Advanced Genetic Analysis : Finding Meaning in a Genome - Scott R. Hawley |
Author |
Scott R. Hawley Michelle Y. Walker
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Cover Price : Rs 495.00
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Imprint : Blackwell Science ISBN : 1405123923 YOP : 2004
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Binding : Paperback Total Pages : 255 CD : No
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DESCRIPTION
Advanced Genetic Analysis brings a state-of-the-art, exciting new approach to genetic analysis. Focusing on the underlying principles of modern genetic analysis, this book provides the how and why of the essential analytical tools needed. The authors vibrant, accessible style provides an easy guide to difficult genetic concepts, from mutation and gene function to gene mapping and chromosome segregation. Throughout, a balanced range of model organisms and timely examples are used to illustrate the theoretical basics
CONTENTS
Preface
Introduction
1. Mutation
2. Mutant Hunts
3. The Complementation Test
4. Suppression
5. Determining When And Where Genes Function
6. Genetic Fine-Structure Analysis
7. Meiotic Recombination
8. Meiotic Chromosome Segregation
Epilogue
References
Index.
ABOUT THE AUTHORS
R. Scott Hawley is a Senior Scientist at the Stowers Institute of Medical Research. Before joining the Stowers Institute in 2001, he was a Professor of Genetics at the University of California at Davis for 10 years. An accomplished textbook author, he has also published over 50 papers and articles in scientific journals. He has also served on the Board of Directors of the Genetics Society of America and is currently on the Editorial Board of Genetics.
Michelle Walker is an Intellectual Property Specialist for Galileo Laboratories in Santa Clara, California. She became interested in law after a brief tenure with the Stowers Institute. She earned an MS in Genetics from the University of California at Davis, has written several scientific articles, served as an Editor for the entomological journal Sociobiology, and spent numerous hours volunteering her time in the field of bioethics and as a scientific mentor for inner-city children. |
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Gene Regulation and Metabolism : Postgenomic Computational Approaches - Collado Vides |
Author |
Collado Vides Ralf Hofestadt
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Cover Price : Rs 495.00
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Imprint : MIT Press ISBN : 9788180520532 YOP : 2004
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Binding : Paperback Total Pages : 310 CD : No
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CONTENTS
Preface
1 Are the Eyes Homologous?
Jeremy C. Ahouse
I Information and Knowledge Representation
2. Automation of Protein Sequence Characterization and its application in whole proteome Analysis
Rolf Apweiler , Margaret Biswas, Wolfgang Fleischmann, Evgenia V. Kriventseva, and Nicola Mulder
3. Information Fusion and Metabolic Network Control Andreas Freier, Ralf Hofestadt, Matthias Lange, and Uwe Scholz
II Gene Regulation : From Sequence to Nework
4. Specificity of Protein DNA Interactions Gary D. Stormo
5. Genomics of Gene REgulation : The View From EScherichia coli Julio collado vides, gabriel moreno hagelsieb , Ernesto Perez Rueda Heladia Salgado, Araceli M Huerta, Rosa Maria Gutierrez, David A Rosenblueth, Andres Christen Esperanza Benitez- Bellon, Arturo Medrano Soto Socorro Gama Castro, Alberto Santos Zavaleta, Cesar Bonavides- Martinez, edgar diaz peredo fabiola sanchez solano and dulce maria millan
6. Discovery of DNA Regulatory Motifs
Abigail Manson McGuire and George M Church
7. Gene Networks Description and Modelling in the GeneNet System
8. Regulation of Cellular States in Mammalian Cells from a Genomewide View
III Postgenomic Approaches
9. Predicting Protein function and Network on a Genomewide scale
10. Metabolic Pathways
11. Toward Computer Simulation of the Whole Cell
Masaru Tomita
Glossary
Corresponding Authors
Index.
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Computational Modeling of Genetic and Biochemical Networks - James M Bower |
Author |
James M Bower Hamid Bolouri
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Cover Price : Rs 595.00
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Imprint : MIT Press ISBN : 978818052051X YOP : 2004
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Binding : Paperback Total Pages : 336 CD : No
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Description
The advent of ever more sophisticated molecular manipulation techniques has made it clear that cellular systems are far more complex and dynamic than previously thought. At the same time, experimental techniques are providing an almost overwhelming amount of new data. It is increasingly apparent that linking molecular and cellular structure to function will require the use of new computational tools.
This book provides specific examples, across a wide range of molecular and cellular systems, of how modeling techniques can be used to explore functionally relevant molecular and cellular relationships. The modeling techniques covered are applicable to cell, developmental, structural, and mathematical biology; genetics; and computational neuroscience. The book, intended as a primer for both theoretical and experimental biologists, is organized in two parts: models of gene activity and models of interactions among gene products. Modeling examples are provided at several scales for each subject. Each chapter includes an overview of the biological system in question and extensive references to important work in the area.
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Microarray Gene Expression Data Analysis : A Beginner's Guide - Helen C Causton |
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Helen C Causton John Quackenbush Alvis Brazma
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Cover Price : Rs 395.00
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Imprint : Blackwell Science ISBN : 140512735X YOP : 2004
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Binding : Paperback Total Pages : 176 CD : No
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DESCRIPTION
This guide covers aspects of designing microarray experiments and analysing the data generated, including information on some of the tools that are available from non-commercial sources. Concepts and principles underpinning gene expression analysis are emphasised and wherever possible, the mathematics has been simplified. The guide is intended for use by graduates and researchers in bioinformatics and the life sciences and is also suitable for statisticians who are interested in the approaches currently used to study gene expression.
Microarrays are an automated way of carrying out thousands of experiments at once, and allows scientists to obtain huge amounts of information very quickly.
Short, concise text on this difficult topic area.
Clear illustrations throughout.
Written by well-known teachers in the subject.
Provides insight into how to analyse the data produced from microarrays.
CONTENTS
Part I: Introduction.
Part II: Aspects Of Experimental Design.
Part III: Data Analysis.
Part IV: Glossary.
ABOUT THE AUTHORS
Helen Causton is an experimental biologist who carried out some of the early studies on genome-wide transcriptional regulation in yeast using microarrays. She is Head of the Clinical Sciences Microarray Centre at Imperial College, University of London.
Alvis Brazma is a computer scientist who has been involved in microarray data analysis since 1998. He heads microarray informatics at the European Bioinformatics Institute and is in charge of establishing a public repository for microarray data.
John Quackenbush is a principal investigator at The Institute for Genomic Research (TIGR). His research interests include development of software for microarray data analysis, gene indices and comparative genomics.
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Prokaryotic Genomics : Methods and Tools in Biosciences and Medicine - Michel Blot |
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Cover Price : Rs 595.00
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Imprint : Springer ISBN : 8181281993 YOP : 2004
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Binding : Paperback Total Pages : 208 CD : No
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DESCRIPTION
Prokaryotic Genomics provides molecular microbiologists in particular and researchers working with bacteria in general with the most important established recipes needed for their work. The volume covers both revisited classical methods and new tools for global analysis such as genomics or proteomics. It is written for those in need of a bench manual to complete their experiments and for those wanting to understand the modern tools used in microbiology.
TABLE OF CONTENTS
1. Physical Analysis of Chromosome size variation
2. Genetic Mapping in Salmonelia enterica
3. Insertion Sequences as genomic Markers
4. The use of noncoding microsatellite Length analysis for Bacterial Strain Typing.
5. How to Amplify Easily, on the Bacterial Chromosome
6. Generalized Transduction
7. Use of Conditional replication, Integration and modular CRIM Plasmids to make single copy lacZ Fusion
8. Genetic Footprinting for bacterial functional genomics
9. Gene Transfer to plants through bacterial vectors
10. Quorum Sensing : Approaches to Identify signals and signalling Genes in Gram negative bactria
11. Transcriptional Profilling in Bacteria Using microarrays
12. Transcriptome Analysis by Macroarrays
13. Prokaryotic Proteomics
14.Intein-mediated protein purification
15. Two-hybrid assay in Esherichia coli K 12
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Evolutionary Genetics : Concepts and Case Studies - Charles W. Fox |
Author |
Charles W. Fox Jason B. Wolf
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Cover Price : Rs 1,295.00
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Imprint : Oxford University Press ISBN : 0195687000 YOP : 2006
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Binding : Paperback Total Pages : 608 CD : No
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REVIEWS
"Evolutionary genetics is an ever-expanding field that treats the fundamental processes of evolution, and so lies at the core of evolutionary biology. Professors Fox and Wolf have convinced many leading international authorities to join them in a comprehensive introduction to the many aspects of evolutionary genetics. Students should find the resulting collection an ideal entry into their studies of evolution."--Douglas J. Futuyma, Distinguished Professor, Department of Ecology and Evolution, State University of New York
"After reviewing the contributions to this excellent volume, I conclude that it is time to rephrase Dobzhanksy's famous quote to say, 'Nothing in biology makes sense except in the light of Evolutionary Genetics!'"--Gunter P. Wagner, Professor of Ecology and Evolutionary Biology, Yale University
"A comprehensive survey of the ideas in the field, by a group of authors that reads like a who's who in evolutionary genetics."--Massimo Pigliucci, Professor of Evolutionary Ecology at State University of New York-Stony Brook, and the author of Phenotypic Plasticity: Beyond Nature and Nurture
"This is a superb survey of the many diverse viewpoints and new developments in a rapidly blossoming field."--Stevan J. Arnold, Professor, Department of Zoology, Oregon State University
CONTENTS
Preface
PART I: Principles of Evolutionary Genetics
PART II: Molecular Evolution
PART III: From Genotype to Phenotype
PART IV: Quantitative Genetics and Selection
PART V: Genetics of Speciation
PART VI: Evolutionary Genetics in Action
Glossary
References
Index.
ABOUT THE AUTHORS
Charles Fox is an evolutionary ecologist who uses quantitative genetic approaches to study evolution and adaptation of ecologically important traits. He has coedited two previous books for Oxford University Press, Maternal Effects as Adaptations (1998) and Evolutionary Ecology : Concepts and Case Studies (2001).
Jason Wolf is an evolutionary geneticist who integrates empirical and theoretical quantitative and population genetics to study the evolution of complex traits. He coedited Epistasis and the Evolutionary Process (2000).
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Principles of Genetics - S.N. Pandey |
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Cover Price : Rs 1,995.00
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Imprint : Ane Books Pvt. Ltd. ISBN : 9789386761231 YOP : 2018
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Binding : Hardback Size : 8.50" X 11.0" Total Pages : 372 CD : No
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About the Book
The book provides a comprehensive coverage on Principles of Genetics and correlated branches in simple and lucid form supported with a large number of self-explanatory illustrations. Subject matter is updated using recent literature. Meant for under-graduate students of Indian Universities and candidates appearing in various competitions, this book will prove immensely valuable to them. Classified features are:
• Describes Cytology, Heredity & Genetics, Molecular Genetics, Biotechnology, Genetic Engineering, Evolution etc. Spread over 35 chapters.
• Special chapters on: Organisation of Genes, Microbial Genetics, Human Genetics, Biotechnology, rDNA Technology, Genetically Modified Organisms (GMOs), Bioinformatics and Proteomics etc.
• Emphasis on check points of various stages in Cell Division, Legality and Utility of GMO crops, Genetic Counselling, Gene Therapy, Applied Biotechnology, Genetic Engineering etc.
• Valuable key notes summarised in boxes in respective chapters.
• Special Glossary of Select Terms. • Study Questions included at the end of each chapter.
Contents
1. The Cell: A Basic Unit of Life 2. Cell Wall and Cell Membrane 3. Cytoplasmic Organelles 4. Non-living Cytoplasmic Inclusions or Ergastic Substances 5. The Structure and Functions of Nucleus 6. The Chromosomes and Nucleosomes 7. Cell Cycle and Cell Division 8. Mendelism: The Nuclear Inheritance (Mendels Laws of Inheritance) 9. Interaction of Genes (Modifications of Mendels Laws) 10. Linkage and Crossing Over 11. Chromosomal Aberrations (Architectural or Structural Changes in Chromosomes) 12. Polyploidy (Numerical Changes in Chromosomes) 13. Extra-nuclear Inheritance (The Organellar Genetics or Cytoplasmic Inheritance) 14. Sex Determination and Sex Reversals 15. Human Genetics 16. Microbial Genetics 17. Mutations 18. Concept of Gene (A Retrospective Approach) 19. Organisation of Genes 20. The Genetic Material 21. DNA : Structure and Replication 22. Ribonucleic Acid: Structure and Transcription 23. Biosynthesis of Proteins 24. Regulation of Gene Activity 25. Population Genetics (Basics) 26. Recombinant DNA Technology 27. rDNA Technology (Retrospects) 28. Genetically Modified Organisms (GM0s) (Transgenic Organisms) 29. Genetically Modified Plants/Crops (Transgenic Plants) 30. Bioinformatics and Proteomics 31. Biotechnology 32. Applied Biotechnology and Genetic Engineering 34. Origin of Life 34. Evidences of Evolution 35. Theories of Organic Evolution, Glossary of Select Terms, Index.
About the Author
Dr. S.N. Pandey, Principal, B.R.D. College, formerly Sr. Reader, Botany Deptt., D.A-V. College, CSJM University, Kanpur, passed M.Sc. (1966) in first division with first position from Agra University and obtained Ph.D from Kanpur University. He has published over 70 research papers in reputed Indian and foreign research journals and has supervised several students leading to Ph.D. degree. While he has co-organised 3 national and 1 international conferences, he has also attended several international conferences including International Botanical Congress, Berlin; Millennium Wetland Event, 2000, Quebec; refresher course with Ducks Unlimited, Canada etc. Besides vast and variegated teaching experience both at UG and PG levels of over 40 years, he has to his credit a few well acclaimed books viz. Plant Physiology, TB of Botany (3 vols.), Advances in Botany (3 vols.), Essential Environmental Studies etc. His academic passion earned him visits to countries like Germany, Austria, Switzerland, France, Italy, USA, UK, Canada etc. He is the Chief Editor of Research Journal of Plant and Environment.
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